Musculoskeletal Histology and Morphometry Core

Director

Deborah Veis
Bone Histology
and Histomorphometry
314-454-8472
dveis@wustl.edu

Specialist

Gretchen Meyer
Muscle Analysis
314-286-1425
meyerg@wustl.edu

Technical Staff

Histology – Crystal Idleburg HT(ASCP)
Sr. Research Tech/Histotech
314-747-6034
idleburgc@wudosis.wustl.edu 

Samantha Coleman
Research Tech II
747-2753
scoleman22@wustl.edu


Billing Administrator

Kami McGhee
Orthopaedic Surgery
314-747-5993
314-454-5900 - fax
kjm@wustl.edu

Overview

The overall objective of the Histology and Morphometry Core is to provide histological services, training and support for the identification and analysis of molecular phenotypes of our target tissues, bone, cartilage, muscle, tendon and ligament, in developing adult mice and other model organisms, as well as patient samples. We aim to achieve this objective by 1) providing high quality, efficient histology services across the range of techniques required for musculoskeletal research; 2) support rigorous and reproducible approaches that contribute to research proposals and publications with high impact; 3) provide training and enrichment opportunities (in concert with the T32 Skeletal Disorders Training Program); 4) enhance and adapt Core services in response to the needs of our Research Community; 5) foster interactions among existing and new members of the Research Community through sharing of techniques and approaches for histology and microscopy.

  • Aim 1 - Histological Services
  • Aim 2 - Resources for Histological Imaging and Analysis
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    The services include:

    1. Preparation of sections for all musculoskeletal tissues (bone, cartilage, tendon, ligament, muscle), including paraffin, methylmethacrylate, and frozen (OCT) embedding and specific tissue orientations, including a variety of specialized stains.
    2. Provision of specialized histology techniques, including nondecalcified frozen sections with tape transfer for fluorescent label visualization, immunostaining, in situ hybridization or laser capture microdissection. Training and protocols can also be provided.
    3. Bone histomorphometry, training and access to equipment.
    4. Consultation on histological techniques and choice of reagents.

    All requests for Core services and equipment scheduling must be made through iLab!

    Click here to Schedule Services

    Special instructions for muscle specimens can be found here


    Click links to view Dr. Veis' presentations

    Bone Histomorphometry 101
    Bone Histomorphometry Guidelines
    What's New in Histomorphometry (2014)
    Concepts in Bone Histomorphometry (2018)

     


     

     

     

    Citing the grant in publications:


    “Washington University Musculoskeletal Research Center (NIH P30 AR057235)”