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Down-regulation of PLCy2-B-catenin pathway promotes activation and expansion of cells in cancer. Capietto, et al. J. Exp. Med. 2013 Oct 21:210(11):2257-71. PMCID: PMC3804931

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Call for Proposals: Pilot & Feasibility Studies

Center for Musculoskeletal Research established at Washington University

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Citing the grant in publications:

“Washington University Musculoskeletal Research Center (NIH P30 AR057235).”


Musculoskeletal Research Center

Washington University Musculoskeletal Research Center

Washington University has a long record of excellence in musculoskeletal research and clinical care.  The MRC Research Base has 75 members who have over 49 million dollars of annual research support (direct costs). The primary goals of the Center are to enhance the productivity of established musculoskeletal scientists, to support young investigators in our field and to facilitate collaboration between established skeletal scientists and those bringing non-traditional questions and strategies to our discipline. The major programmatic focus of the MRC will be to support and expedite the creation and analysis of animal models of relevance to musculoskeletal biology and disease. Our basic and translational research efforts will be directed toward an understanding of musculoskeletal biology at the molecular, cellular and tissue levels with the goal that such studies will directly impact our understanding of the pathophysiology of osteoporosis, osteoarthritis, muscular dystrophy, osteochondrodysplasias as well as regeneration of bone, cartilage, tendon and muscle.

Musculoskeletal Research Center

In January 2012, the Department of Orthopaedic Surgery and the Department of Internal Medicine, Division of Bone & Mineral Disease, joined forces in the BJC Institute of Health building, forming the nucleus of the Musculoskeletal Research Center.
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On May 23, 2012, we celebrated the official opening of the Musculoskeletal Research Center. (Click here for pictures of the opening)

Just in Time Funding now available! Click here for details.
Teams in Translational Musculoskeletal Research Funding now available! Click here for details.